What types of birth defects in children have been associated with Zofran usage?

What types of birth defects in children have been associated with Zofran usage? Recently, the correlation between mothers taking Zofran and their children being born with birth defects has grown more conspicuous. Here are some of the most common birth defects currently associated with Zofran:

  • Cleft Palate: This condition occurs when the roof of the mouth does not completely form, and the two skull plates that are supposed to fuse to form the hard palate do not do so. There are complete and incomplete forms of these conditions, but both are serious. They both result in a hole between the nose and mouth that can cause extraordinary nasal and articulation issues.
  • Cleft Lip: Cleft lip conditions closely resemble those of cleft palates. This condition occurs when the lip does not properly form either because of an underlying genetic abnormality or because of an isolated trigger. These are more common than palate problems and, after surgery to fuse the lip together, require minimal care or attention. Left untreated, however, this can cause extreme eating, speaking, and related social and psychosocial problems.
  • Heart Abnormalities: Several heart abnormalities in children have been associated with the use of Zofran by their mothers. One of the most serious and recurring is Atrial Septal Defect (also known as “hole in the heart” syndrome). This occurs when a hole in the upper two chambers of the heart allows blood to pass back and forth. Another defect children experience is Ventricular Septal Defect: a leak in the bottom two chambers of the heart that allows blood to leak between the two. While the latter is less common, both can lead to life-threatening medical issues. Finally, children with mothers who were prescribed Zofran have experienced heart murmurs.

So far, studies have only conclusively shown a correlation between Zofran and these birth defects. However, the association is conspicuous as children born to mothers prescribed this medication exhibit these conditions at a rate twice that of mothers that do not take it. Also, these are not minor or small studies; the below represents significant and scholarly work:

Finally, and maybe most troubling, Zofran can transfer from the mother to the child via the placenta up to the first three months following conception.

For additional information see the following pages:

Client Reviews
Jonathan Rosenfeld was professionally objective, timely, and knowledgeable. Also, his advice was extremely effective regarding my case. In addition, Jonathan was understanding and patient pertaining to any of my questions or concerns. I was very happy with the end result and I highly recommend Jonathan Rosenfeld.
★★★★★
Extremely impressed with this law firm. They took control of a bad motorcycle crash that left my uncle seriously injured. Without any guarantee of a financial recovery, they went out and hired accident investigators and engineers to help prove how the accident happened. I am grateful that they worked on a contingency fee basis as there was no way we could have paid for these services on our own. Ethan Armstrong, Google User
★★★★★
This lawyer really helped me get compensation for my motorcycle accident case. I know there is no way that I could have gotten anywhere near the amount that Mr. Rosenfeld was able to get to settle my case. Thank you. Daniel Kaim, Avvo User
★★★★★
Jonathan helped my family heal and get compensation after our child was suffered a life threatening injury at daycare. He was sympathetic and in constant contact with us letting us know all he knew every step of the way. We were so blessed to find Jonathan! Giulia, Avvo User
★★★★★
Jonathan did a great job helping my family navigate through a lengthy lawsuit involving my grandmother's death in a nursing home. Through every step of the case, Jonathan kept my family informed of the progression of the case. Although our case eventually settled at a mediation, I really was impressed at how well prepared Jonathan was to take the case to trial. Lisa, Avvo User
★★★★★
Contact Us for a Free Consultation (888) 424-5757
Chicago Office Map