What is Invokana?
Invokana is a drug that is used to treat type-2 diabetes. It is know by the medical moniker Canagliflozin. It was created by Mitsubishi Tanabe Pharma and is marketed and distributed by Janssen, a subsidiary of Johnson & Johnson. Since its primary target is those afflicted with type-2 diabetes, here are some statistics on that segment of the population:
- Almost 30 million people have type-2 diabetes in America.
- Over 200,000 people under the age of 20 have type-2 diabetes.
- Over 80 million adults have prediabetes, a blood sugar condition which verges upon type-2 diabetes.
- Nearly 25% of the elderly population has type-2 diabetes.
- Over 1.5 million people develop type-2 diabetes every year.
- Type-2 diabetes costs the American medical system over $200 billion every year.
- Factors that are associated with type-2 diabetes include family history, diet, age, weight, and exercise regimen.
Invokana is supposed to work by lowering the blood sugar in the body. It does this by triggering its exit through urine and because of this it is known as an SGLT2 inhibitor (also called gliflozins). However, it is not the only one and others include Xigdup XR, Invokamet, Farxiga, Glyxambi, and Jardiance. While some of these may operate a bit different, they all have the primary purpose of lowering glucose levels.
Many SGLT2 inhibitors have exhibited problems in patients that have been prescribed them. Here is an incomplete but pertinent list of some of their side effects including those found in Invokana:
- High cholesterol.
- Yeast infections.
- Urinary tract infections and inflammation.
- High potassium.
- Kidney disease.
Maybe the problems found within Invokana should have been foreseen and fixed before they could have harmed patients. The company that currently markets and distributes Invokana, Janssen Pharmaceuticals, stated that patients given it during clinical trials developed ketoacidosis. Ketoacidosis is a complication of diabetes where the body improperly and disproportionately produces blood acids called ketones. Unfortunately, it still cleared FDA hurdles and obtained approval for mass distribution and sale.
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