Invokana (canagliflozin) is a popular prescription medication used to treat type II diabetes. Unfortunately, many patients who have taken the medication have suffered severe side effects that include ketoacidosis and a foot or leg amputation. Individuals who have been injured by Invokana (canagliflozin), Invokamet (canagliflozin and Metformin) or Invokamet XR (canagliflozin and Metformin hydrochloride extended-release) might be entitled to file a case for compensation against the drug manufacturer to recover damages.
Rosenfeld Injury Lawyers LLC represents victims of defective medications and other types of professional negligence. Our law firm has successfully prosecuted cases for our clients who were injured by negligent pharmaceutical manufacturer that made and distributed a dangerous drug. Our attorneys are available to answer any legal questions on how to receive the monetary compensation you deserve if your injuries were a result of someone else's negligence. Should you have additional questions, we invite you to contact our office for a free review of your legal rights.
How Much is my Case Worth?
The extent of your injuries and the facts and evidence involved in your case are unique compared to all the lawsuits involving damage caused by Invokana (canagliflozin). However, your attorney can use proven methods to accurately calculate the value of your case.
Because your lawyer will file your Invokana lawsuit as a products liability case, your damages will probably be compensatory in nature. Compensatory damages are meant to repay plaintiffs for the losses that defendants have wrongfully inflicted upon them. Some examples of these losses include:
- Current, past, and future medical expenses
- Hospital costs associated with your injuries
- Lost wages from time away from work
- Loss of future earnings if you are unable to return to your previous occupation,
- The need for long-term health care,
- Support damages required to prepare meals, to your chores, and care for your children that you can no longer perform because of your injuries.
- Funeral and burial costs if you lost a loved one because of an Invokana injury.
- Non-economic damages including pain, suffering, mental anguish, emotional distress, and anxiety associated with your Invokana-associated injuries.
Of course, in any products liability case, you can always recover for the value of the damaged item itself. See Suvada v. White Motor Co., 32 Ill.2d 612 (1965). According to the "Moorman" doctrine, if plaintiffs can prove an underlying injury, then they can also plead economic losses in products liability cases. See Moorman Mfg. Co. v. Nat'l Tank Co., 61 Ill. Dec. 746 (1982).
Seeking economic damages attempts to compensate plaintiffs for the financial loss a particular injury has caused them. Unlike compensatory damages, these are much harder to point to and calculate. Thus, courts are less likely to let them come into litigation if there are no obvious compensatory damages.
FDA Approval of Invokana
In 2013, the FDA (Food and Drug Administration) approved Invokana as a type two diabetes medication because of its SGLT-2 (sodium-glucose cotransporter 2) inhibiting properties. SGLT-2 is a human protein known to facilitate the reabsorption of glucose in the kidneys. The inhibiting properties of Invokana (canagliflozin) can block glucose reabsorption in the kidneys and lower the body's blood glucose levels.
The research submitted to the FDA along with the results of clinical trials have revealed that Invokana (canagliflozin) and other competitive SGLT-2 medications can control blood glucose levels and lower hemoglobin levels in type two diabetic patients. While the medication has remained popular as an effective treatment for type II diabetes, scientists have linked the drug to many potentially dangerous adverse health effects.
In 2016, the federal regulatory agency released a safety communication warning to alert the public that taking Invokana (canagliflozin), Invokamet, or Invokamet XR increased potential risk of the consumer needing a leg or foot amputation. Less than a year later, the FDA released a follow-up safety warning that alerted consumers that taking Invokana nearly doubled the potential risk of amputation in diabetic patients compared to other people with diabetes that did not take Invokana or its generic form canagliflozin.
The FDA has since issued warnings as evidence identified by CANVAS and CANVAS-R studies citing that Janssen failed to warn consumers about the potential risk of taking the drug. Instead, the pharmaceutical giant continued to market and promote their drug as being safer for diabetic patients and at times promoted the medication for off-label purposes to improve cardiovascular function, reduce blood pressure, and treat weight loss.
Some to the plaintiffs filing lawsuits against Janssen pharmaceuticals state that had they been warned of the increased potential risk of needing an amputation they would not have taken the medication but chose another option. These injured victims state that they did not receive pertinent information to make the most-informed choice on what to do because the evidence was hidden from them by Janssen.
- May 2015 – The FDA begins receiving reports that some patients taking Invokana (canagliflozin) have been diagnosed with ketoacidosis and diabetic ketoacidosis (DKA) that required hospitalization. This condition reduces the release of insulin that at low levels can no longer generate a fuel source by breaking down glucose (sugar) when the body must begin breaking down fats for energy.
- September 2015 – The federal agency informs Janssen that they must update their warning label to add the increased potential risk of consumers taking Invokana suffering a bone fracture.
- December 2015 – The FDA informs the drug maker that they must change their warning label to state that Invokana (canagliflozin) can increase the potential risk of developing ketoacidosis and severe urinary tract infections (UTIs). Many of these injured patients suffered serious side effects caused by blood infections that included increase heart rate, chills, and fevers.
- 2016, the FDA begins receiving reports of Invokana users experiencing acute pancreatitis after they were diagnosed with an inflamed or swollen pancreas and could no longer produce needed insulin. Some of the patients experienced severe health issues, and others died.
- May 2016 – The federal regulatory agency issues of public response to the CANVAS and CANVAS-R studies by initiating an amputation warning when consumers use the drug.
- June 2016 – The FDA initiates a safety communication to doctors to include a stronger warning concerning the potential risks of Invokana users developing severe kidney injuries. Many of these Invokana (canagliflozin) users develop severe conditions including coma, seizures, swelling, confusion, and nausea.
- May 2017 – The federal agency releases a follow-up amputation warning telling Janssen that they must update their Black Box Warning Label immediately.
Invokana Problems Have Been a Serious Concern
Thousands of patients have filed Invokana lawsuits against Janssen Pharmaceuticals, a subsidiary of Johnson & Johnson. Many of these plaintiffs allege that they suffered adverse side effects including amputation after taking the medication. Some cases are filed on behalf of deceased patients who passed away after taking the drug.
Attorneys working on behalf of the plaintiffs have alleged that Janssen failed to warn doctors and consumers of the potential risk of taking the medication. Invokana problems are nothing new. For years, the drug manufacturer knew from clinical trials that patients taking the medication were twice as likely to require a foot or leg amputation compared to patients who received a placebo.
Invokana-Related Adverse Effects
Doctors often prescribe Invokana (canagliflozin) as a 100 mg dose taken once each day, preferably before breakfast. Some patients take up to 300 mg. Unfortunately, some patients experienced a severe reaction when taking Invokana (canagliflozin) with digoxin or rifampin used to treat heart rhythm problems and blood pressure issues. Common side effects associated with taking Invokana (canagliflozin) include:
- Vaginal itching,
- Yeast infections of the vagina, vulva, or penis
- Increase urination volumes,
- Urinary tract infections (UTIs),
- Weakness and fatigue,
- Kidney issues,
- Bone fractures,
- Hypersensitivity reaction including swelling, hives, itching, rash, and skin redness,
- Skin sensitivity to daylight,
- Low blood sugar levels,
- Extreme loss of retained fluids,
- Dry mouth and excessive thirst,
- High cholesterol levels,
- Elevated levels of phosphate in the bloodstream,
- Acute kidney failure,
- Elevated levels of hemoglobin,
- Kidney disease caused by reduced renal function,
- Decreased density or calcification of bone tissue,
- Intense abdominal pain,
Other SGLT-2 Medication Warnings
Nearly immediately after the FDA approved Invokana, other companies began applying for approval of their SGLT-2 class medications through the federal agency's fast-track program. The FDA can push other similar drugs to the approval process if the competitive medication shares the same formulated ingredients. Other drugs that share the same properties as Invokana (canagliflozin) include:
- Xigduo XR
The FDA initially approved Farxiga for availability in the medical marketplace in 2014. Originally, the medication was rejected for approval by the federal agency in numerous pre-market trial phases. This medication shares similar ingredients and formulation compared to other highly popular SGLT-2 inhibitors including Invokana (canagliflozin). However, the drug has unique side effects including the potential of causing bladder cancer at a rate five times higher than other SGLT-2 inhibitors drugs. The Cancer Prevention and Treatment Fund conducted a study that revealed that Farxiga might also advance existing bladder cancers inpatient suffering from the condition.
Building a Case for Compensation
Thousands of patients have filed Invokana lawsuits in multidistrict litigation courts. The suits are filed against Janssen Pharmaceuticals, a subsidiary of Johnson & Johnson. The claims for compensation allege that the drug maker:
- Designed, manufactured, marketed, promoted, and distributed a defective and dangerous drug.
- Placed unsuspecting patient at risk of ketoacidosis, and kidney failure and amputation.
- Never warned consumers that they knew there were potential risks for taking the dangerous drug.
- Failed to test the medication for any potential side effects before releasing it in the medical marketplace.
- Withheld evidence from the FDA, doctors, and consumers that they knew their drug was dangerous and yet said nothing, which led to the injury and death of thousands of Invokana takers.
Currently, thousands of lawsuits have been filed in a New Jersey federal courthouse for multidistrict litigation (MDL #2750). The federal judge handling the case has scheduled the first bellwether trials that will likely start in September 2018. Other Invokana (canagliflozin) lawsuits are still pending in California, and Missouri federal courtrooms in individual cases are being heard in Pennsylvania, California, and New Jersey state courts.
If you suspect that you are the victim of an Invokana injury, taking action quickly as your best legal option. All necessary documents and paperwork must be filed in the proper courthouse before the state, or federal statute of limitations concerning your case expires.
Attorneys Handling Invokana Lawsuits
The Invokana injury attorneys at Rosenfeld Injury Lawyers LLC understand that your injuries are not your fault but the responsibility of the pharmaceutical manufacturer who made and distributed a defective drug. Our law firm has successfully obtained millions on behalf of the victims and their family members to ensure they were adequately compensated to cover their medical expenses, household bills, lost wages, loss of future earnings, pain, suffering, and emotional damage and qw can help your family too.
Our legal team encourages you to contact our attorneys today to schedule a no-obligation case consultation to discuss the merits of your monetary recovery claim at no charge to you or your family. Our attorneys accept all personal injury cases, wrongful death lawsuits, and defective medication injury claims through contingency fee arrangements. This legal contract postpones the payment of legal services until after we have successfully completed your case through a negotiated settlement or a jury verdict.
Our law firm gets results quickly because we understand you need money now. We proudly offer every client a “No Win/No-Fee” Guarantee, meaning if we are unable to secure financial compensation on your behalf you owe us nothing. All information you share with our law office will stay confidential.
For additional information see the following pages:
- What is Invokana?
- What are the risks of taking Invokana?
- Has the FDA taken any action against the makers of Invokana?
- What does an Invokana lawsuit look like?
- What are the laws surrounding Invokana?
- Have there been any cases or settlements involving Invokana?
- Is there a time limit by when I have to file my Invokana lawsuit?
- Is there a class action lawsuit against Invokana?
- Why hire Rosenfeld Injury Lawyers LLC?