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Zantac Stomach Cancer Lawsuits

Stomach cancer is a serious disease that can be deadly. The American Cancer Society (ACS) estimates that in the year 2022, nearly 28.000 men and women will be diagnosed with stomach cancer, and about 11,000 will die from it.

Now, there is concern that these medications could increase the risks of developing cancers, including cancer of the stomach. If your doctor diagnosed you with cancer that was likely caused by medication, such as Zantac, the personal injury attorneys at Rosenfeld Injury Lawyers, LLC, can help ensure you receive the financial compensation you deserve.

Contact our dangerous drug attorneys at (888) 424-5757 or use the contact form for immediate legal advice or schedule a free consultation. All confidential or sensitive information you share with our legal team remains private through an attorney-client relationship.

stomach cancer lawsuits

Cancer of the stomach can be a life-threatening disease that starts in mucus-producing cells in the stomach lining.

Often referred to as adenocarcinoma or gastric cancer, stomach cancer involves malignant cells that slowly form gastrointestinal carcinoid tumors, lymphomas, or gastrointestinal stromal tumors over many years.

Scientists believed H. Pylori bacterial infections cause gastric cancers.

Metastasized Cancers

Stomach cancer tends to spread (metastasize) through the stomach's walls to affect adjoining organs, including the spleen and pancreas, and eventually into the lymph nodes. Once the cancerous cells reach the bloodstream, they can spread to distant organs, including the lungs, bones, and liver.

Medical science advancements have reduced the incidence of death rates associated with stomach (gastric) tumors over the last six decades in America. Back in the 1930s, cancer in the stomach was the leading cause of death of American men who died of some form of cancer.

Over the last 90 years, the death rate involving stomach (gastric) cancer has dropped markedly. It is thought to result from advancements in medical technology and better forms of treatment.

Stomach tumor lawsuits are all over the news. It's not surprising when you think about it since stomach cancer is so deadly. Recently, we have learned that a stomach tumor lawsuit could be filed due to regular exposure to high levels of chlorine.

Proton Pump Inhibitors

Proton pump inhibitors (PPI)  have been a mainstay of treatment for decades, but a link to a rare form of stomach tumor has prompted lawsuits against the makers of drugs such as Nexium, Prilosec, and Prevacid.

Our lawyers are prosecuting stomach cancer cases. Learn about Zantac lawsuits and Philips CPAP lawsuits on the specific practice pages, or contact us toll-free at (888) 424-5757 for an initial consultation about your legal options.

Zantac Stomach Cancer Lawsuits

Zantac stomach cancer lawsuits are currently being filed by people diagnosed with stomach cancer after taking the medication Zantac. In addition, the drug company GlaxoSmithKline faces Zantac stomach cancer lawsuits for failure to disclose the risks and dangers associated with the drug.

There are currently over 500 Zantac stomach cancer lawsuits pending all across the United States. Hundreds of these claims have been filed against GlaxoSmithKline. The Zantac lawsuits are worth watching because they address several issues that affect drug manufacturers, consumers, and the pharmaceutical industry in America.

A Zantac lawsuit is the current subject of recent news reports. If you or a loved one has taken Zantac for acid reflux and suffered severe side effects, you may be entitled to compensation. In addition, if the drug was prescribed to you or a family member, there is a time limit for filing a Zantac lawsuit against the drug company.

A harmful drug lawsuit in a district court in New Jersey got national attention after a jury awarded $1.5 million to a plaintiff who took Zantac for four days and suffered severe damage to his esophagus.

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Online Pharmacy Valisure Lawsuit

Online Pharmacy Valisure has come under fire concerning stomach tumor lawsuits. The United States Food and Drug Administration (FDA) has accused the company of distributing fake medications.

The agency claims that Valisure failed to obtain prescriptions from customers and that it sold prescription-strength ibuprofen, which is a nonsteroidal anti-inflammatory drug.

Multidistrict Litigation in Stomach Tumor Cases

Multidistrict litigation is a special procedure in civil litigation where specific actions, filed nationwide or against multiple defendants, will be consolidated and heard at one federal court. Usually, it's defined as class actions involving 50 or more plaintiffs in one court.

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Who is at Risk for Stomach Cancer?

While anyone can develop a stomach tumor, certain risk factors increase the risk of developing the disease. In certain parts of the world, including Latin America, Eastern Europe, Korea, China, and Japan, stomach cancer ranked second of all cancer-related deaths around the globe.

The most widely known exposure factors associated with stomach cancers involve:

  • Gender: Being male significantly increases the individual's chances of developing cancer of the stomach.
  • Age: Being older increases the exposure of developing the disease.
  • Smoking Tobacco Products
  • Consuming a diet deficient in vegetables and fruit but rich in meat, smoked fish, poorly preserved foods, and salty food
  • Pernicious Anemia: Individuals that have been previously diagnosed with chronic progressive disease pernicious anemia are more likely to develop stomach tumors because of their inability to absorb vitamin B12.
  • Benign Duodenal or Stomach Ulcer Disease: Patients who had a portion of their stomach removed to treat ulcers in the duodenum or stomach have increased exposure to develop stomach tumors in the remaining organ, especially if 15 years or more have passed after the surgery.
  • Genetic Predisposition: Individuals with a family history of stomach cancer are more exposed to developing the disease.
  • Blood Type A: People with Blood Type A are more exposed than those with Blood Type O, B, or AB.
  • Defective Pharmaceutical Drugs: Including Valsartan and Zantac
  • Occupations: There is an increased risk of stomach tumors among those employed in the maritime industry.

According to a new study, nonsteroidal anti-inflammatory drugs increase the risk of stomach tumors among people who use nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and aspirin.

Other exposure factors associated with the personal medical history can negatively impact the exposure of developing cancer of the stomach.

These include:

  • Excessive alcohol consumption
  • Consuming too much meat, processed foods, or salty foods
  • Neglecting to exercise regularly
  • Not properly storing or cooking food

The doctor may recommend a screening test to determine if the patient can develop stomach cancer. The test works well for individuals with exposure who might not yet be experiencing common symptoms associated with the disease.

Taking Zantac and Prilosec to treat occasional heartburn and other stomach problems may not be worth it for people who already have high exposure to develop stomach tumors.

The gastrointestinal conditions known to have higher exposure to stomach tumors include ulcerative colitis, Crohn's disease, pernicious anemia, and hereditary syndromes.

Taking Zantac could increase the risk of developing a stomach tumor. According to personal injury lawsuits filed against Pfizer and GlaxoSmithKline (GSK), the makers of the popular heartburn medicine, Zantac can cause stomach malignancy.

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Common Symptoms of Stomach Tumors

Many of the initial symptoms of stomach tumors in their early development are nonspecific and vague. However, during its onset, the individual might notice certain specific symptoms that include:

  • Difficulty when swallowing due to the development of a tumor close to the esophagus in the upper portion of the stomach
  • Frequent heartburn
  • Mild discomfort in the upper abdominal region leads to a loss of appetite and nausea
  • Constant bloating
  • Stomach Pain that becomes significantly worse after consuming meals
  • Early Satiety - Feeling full after consuming a small amount of food
  • Jaundice where the eyes and skin take on a yellowish discoloration

As the disease progresses, the symptoms often exacerbate and lead to:

  • Unexpected weight loss
  • Excessive fatigue
  • Severe vomiting and nausea due to some form of blockage that does not allow the stomach to drain
  • Excessive blood loss includes passing dark black blood-digested stools, vomiting blood, or a substance that appears like coffee grounds
  • Iron deficiency anemia leading to low red blood cell numbers

Diagnosing Stomach Cancer

Many people suffering from stomach tumors do not experience any symptoms when the disease is caught early. As a result, doctors typically diagnose stomach cancer after the disease has progressed significantly.

The physician will conduct a comprehensive physical examination to validate a diagnosis to look for any abnormality. Usually, a blood test will be ordered to identify the presence of a Helicobacter Pylori bacterial infection that is thought to cause many gastric cancers.

Any indicators of the presence of stomach tumors usually require further diagnostic testing that can identify suspected tumors or any other associated abnormality of the esophagus and stomach. Some of these tests could include:

  • A Biopsy: The doctor will collect a tissue sample, usually through fine needle aspiration, where a long fine needle is inserted through the abdominal wall to collect a small sample of stomach tissue that a pathologist can analyze under a microscope in a laboratory setting.
  • Imaging Tests: The physician may order an x-ray, PET scans, CT (computerized tomography) scans, or MRI (magnetic resonance imaging) scans that provide detailed images of the stomach, pelvis, and abdomen to identify a cancerous abnormality mass or tumor.
  • Upper Endoscopic Test: The doctor can insert a thin tube with an attached camera into the throat to enter the stomach and look for any suspicious tissue that can be collected (biopsy) for analysis.
  • Exploratory Surgery: A surgeon can perform exploratory surgery (laparoscopic) to see if cancer has spread (metastasized) beyond the stomach or esophagus and reached the abdomen or thoracic cavity. Usually, this procedure involves making several small incisions in the abdominal wall before inserting a special camera that collects and transmits images to an operating room monitor.
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Staging

After a diagnosis of the stomach and the tumor is verified, the doctor will need to stage the stomach cancer to determine its progression before developing an effective care plan for treating the disease. These four stages include:

  • Stage I: In the initial stage, the disease only affects the stomach or esophagus and possibly spreads to neighboring lymph nodes.
  • Stage II: As the disease progresses, it moves deeper into the muscle layers of the stomach wall or esophagus and possibly into additional lymph nodes.
  • Stage III: Cancer has reached neighboring structures and affects the lymph nodes more extensively at this highly progressive stage.
  • Stage IV: At its most progressive stage, cancer has metastasized to distant sites throughout the body, possibly to the lungs, liver, breast, bones, or brain.

Our law firm is interested in speaking with individuals treated for stomach tumors (also referred to as gastric cancer) and not warned about the exposure of developing second cancer in the stomach known as "Adenocarcinoma of the Gastric Body" (AG Body).

If you or a loved one was diagnosed with a stomach tumor and not warned about this exposure, please call us at (888) 424-5757 for a free consultation to facilitate your legal help.

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Types of Stomach Cancers

Gastric Cancer

Gastric cancer is a tumor that arises from cells of the stomach. The gastric tumor is the fourth leading cause of cancer-related deaths worldwide.

More than half a million new cases are reported annually, and almost half of these cases are in China. The 5-year survival rate is 20-25% of all gastric cancer patients and even lower among those with more advanced disease.

The risk of gastric erosion from chronic use of Zantac has been reported. In 1992, a woman was started on oral Ranitidine (1) to treat "trigeminal neuralgia." After several weeks of use, the patient experienced persistent epigastric pain and anemia.

Liver Cancer

Liver cancer is the name of a range of different cancer types which can grow in the liver.

Esophageal Cancer

Esophageal cancer is a cancerous tumor that arises from the esophagus or food pipe. The symptoms are not specific, so it is frequently diagnosed late in the advanced stages.

The esophagus is a muscular tube that runs from the pharynx to the stomach. During swallowing, food passes from the back of the mouth down the esophagus, where it enters the stomach.

Pancreatic Cancer

Pancreatic cancer is a cancer of the pancreas that begins in the tissue of the pancreas. Symptoms may include pain, weight loss, and vomiting.

Gastrointestinal Cancer

Gastrointestinal Cancer (GI) starts in the stomach, colon (intestines), rectum, liver, pancreas, gallbladder, or bile ducts.

The symptoms of gastrointestinal cancer are varied but often may include weight loss, abdominal pain, vomiting, and diarrhea. Gastrointestinal Cancer can be serious because it is hard to detect early.

Many factors can lead to Gastrointestinal cancers, for example, smoking, being obese, poor diet, alcohol intake, bacteria in the gut, and even certain infections. However, it is not so simple to pinpoint what exactly causes them because often, people with these factors don't get GI cancers.

Bladder Cancer

Bladder cancer is the fourth most common type of cancer in men and women. This year, nearly 70,000 people will be diagnosed with bladder tumors in the United States of America, mainly older men.

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Staging

After a diagnosis of stomach cancer has been verified, the doctor will need to stage the stomach cancer to determine its progression before developing an effective plan of care for treating the disease. These four stages include:

  • Stage I – In the initial stage, the disease only affects the stomach or esophagus and possibly spread to neighboring lymph nodes.

  • Stage II – As the disease progresses, it moves deeper into the muscle layers of the stomach wall or esophagus and possibly to additional lymph nodes.

  • Stage III – At this highly progressive stage, the cancer has now reached neighboring structures and effects the lymph nodes more extensively.

  • Stage IV – At its most progressive stage, the cancer has metastasized to distant sites throughout the body, possibly to the lungs, liver, breast, bones, or brain.
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Probable Human Carcinogen

A probable human carcinogen is a designation assigned to chemicals or groups of chemicals shown by epidemiological evidence to cause cancer or statistically significant increases in the incidence of tumors.

The increased risk of gastric tumor development increased with acid-inhibiting drugs (AID) consumed.

Ranitidine Products and Cancer Exposure

Ranitidine products are used to treat or prevent ulcers, gastro-esophageal reflux disease, heartburn, and stomach inflammation.

These are prescription medications that are available in pill form. Some of the most common brands that contain Ranitidine are Zantac, Zantal, and Ranmax.

Studies show that ranitidine products are linked to stomach tumors. The studies also show that patients taking the drug for heartburn or ulcers are at a greater exposure of developing stomach tumors, especially if they have also been exposed to nitrates.

Taking Ranitidine can increase the risk of a cancerous tumor in the stomach known as a 'gastric adenocarcinoma' or a 'gastro-esophageal junction carcinoma.'

If you developed stomach cancer, our attorneys want to help you file drug injury lawsuits to recover compensation.

Treating the Stomach Tumor

The doctor typically has distinct options for treating stomach tumors at all phases and progressions of the disease. It includes surgical procedures, radiation therapy, chemotherapy, targeted medications, and palliative (supportive) care at the final stage of stomach tumors when every other appropriate treatment is no longer effective.

It includes surgical procedures that remove tumors, portions of the stomach, lymph nodes, or the entire stomach when necessary. Radiation uses x-ray technology to destroy tumor cells, while chemotherapy uses chemical medications to kill cancer cells.

Targeted Therapies

Targeted therapy uses specialized drugs that destroy abnormal cells and is often used in conjunction with standard chemotherapy medications. The early stages of cancer are not always easy to detect.

The risk of gastric cancer increases in patients with Barrett's esophagus, although the absolute exposure of developing it is low despite chronic exposure to acid-peptic products.

If a harmful medication is left unchanged for a long time, making the patients understand that they should stop using it may be challenging. It could lead to severe consequences because the patients could get dependent on the medication.

COX-2 Inhibitors

A patient is at a higher risk if their medication is a nonsteroidal anti-inflammatory medication. The class of drugs includes over-the-counter medications such as ibuprofen, naproxen, diclofenac, and prescription medications such as COX-2 inhibitors (coxibs). These can cause ulcers and stomach bleeding that can lead to cancer.

A Ranitidine study published in the "Annals of Epidemiology" in 2002 stated that taking over-the-counter doses of Ranitidine medication for heartburn or acid reflux was associated with an increased risk for stomach tumors in women.

Other Health Implications Due to Dangerous drugs

Approximately 20% of new chronic kidney disease (CKD) cases are due to medications. In addition, in a hospital-based case-control study of 29,769 hospitalized patients with acute kidney injury, the use of statins has been associated with a significant increase in the exposure of acute kidney injury.

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The Food and Drug Administration is Monitoring Harmful Medications

The FDA has announced that they will start actively monitoring postmarketing reports of gastric tumors in patients taking the COX-2 inhibitor drug class, including Celebrex (celecoxib), Bextra (valdecoxib), and Vioxx (rofecoxib).

In addition, FDA recalls are expanding the number of people who must watch their food intake.

World Health Organization Position on NDMA

World Health Organization Position on NDMA is as follows: "N-nitroso compounds are a group of carcinogenic chemicals whose most frequent use is as preservatives in processed meats.

In the stomach, these chemicals may produce mutagenic effects both by direct reaction with DNA and indirectly through activation of the endogenous enzyme system. Therefore, a stomach tumor is connected with the ingestion of this class of chemicals.

NDMA is not carcinogenic, but it is converted into a mutagenic compound after ingestion into the gastrointestinal tract. Therefore, ingestion of nitrosamines from cigarette smoke is probably of less importance."

Mutagenic Compound NDMA

In conclusion, the WHO has found that NDMA is a mutagenic compound that, when ingested into the gastrointestinal system, has produced carcinogenic effects and increased the risk of stomach tumors.

Hiring a Personal Injury Attorney to Resolve a Cancer Compensation Case

If you or a loved one developed a stomach tumor after taking Valsartan or similar medications, you might be entitled to pursue a Valsartan lawsuit. Please visit our Valsartan litigation page for more information or call our law office at (888) 424-5757 to schedule a free case evaluation.

We accept all cases on a contingency fee basis, meaning we are only paid if we secure compensation on your behalf.

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